Details-Calcnet-AlzheimerNet

Target name

P05230: Fibroblast growth factor 1

Protein function

Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.

Database links

Uniprot primary ID	P05230
PDB ID	3FJA 3FJC 3FJB 3FJE 3FJD 3FJF 1AXM 3FJH 2AFG 3FJJ 4Q9P 4QO3 1Q04 3UD7 1Q03 3CRG 3CRH 4Q9G 1JTC 3UD8 3UD9 3BAU 3BAV 3BAQ 1Z2V 2RQ9 1E0O 3BAD 3FJI 3BAG 3BAO 3BAH 3FJK 3BA4 3BA5 3BA7 3O3Q 3FGM 2ERM 3CRI 1JQZ 3CQA 1Z4S 3BB2 1QCT 2AQZ 3UDA 1EVT 2HZ9 4QAL 3HOM
DrugBank ID	DB06589 DB01025 DB00686
BioGrid ID	108537
GuidetoPHARMACOLOGY ID
PharmGKB ID	PA28105
KEGG ID	hsa:2246
BioCyc
Entrez Gene (Gene ID)	2246
DIP	DIP-3787N
STRING	9606ENSP00000338548
MINT	MINT-118570
IntAct	P05230
DMDM	122737
BREDNA
Rectome	R-HSA-5654221 R-HSA-190377 R-HSA-190375 R-HSA-190372 R-HSA-190373 R-HSA-5654227 R-HSA-190371 R-HSA-5654720 R-HSA-5654228 R-HSA-5654689 R-HSA-5654688 R-HSA-2219530 R-HSA-5654726 R-HSA-5654727 R-HSA-5654219 R-HSA-5654700 R-HSA-1257604 R-HSA-56 R-HSA-5673001
SignaLink	P05230
BindingDB	P05230

Model Performance Metrics

Fingerprint type	F1_CV	AUC_CV	Accuracy_CV	Sensitivity_CV	Specificity_CV	F1_test	AUC_test	Accuracy_test	Sensitivity_test	Specificity_test	Download model
FP2 fingerprints	0.853	0.868	0.847	0.887	0.806	0.867	0.863	0.871	0.867	0.875	Download
MACCS fingerprints	0.730	0.856	0.748	0.689	0.806	0.813	0.867	0.806	0.813	0.800	Download
Daylight fingerprints	0.793	0.823	0.798	0.774	0.823	0.828	0.838	0.839	0.800	0.875	Download
ECFP2 fingerprints	0.667	0.822	0.702	0.597	0.806	0.897	0.960	0.903	0.867	0.938	Download
ECFP4 fingerprints	0.860	0.928	0.863	0.839	0.887	0.897	0.956	0.903	0.867	0.938	Download
ECFP6 fingerprints	0.857	0.935	0.871	0.774	0.968	0.889	0.965	0.903	0.800	1.000	Download

Download datasets

Positive dataset

Negative dataset