Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids (PubMed:
| Uniprot primary ID | P08473 |
| PDB ID | 2QPJ 1DL9 1DMT 1QVD 2YB9 4CTH 1R1J 1R1H 1R1I 1Y8J |
| DrugBank ID | DB00616 DB06655 |
| BioGrid ID | 110455 |
| GuidetoPHARMACOLOGY ID | 1611 |
| PharmGKB ID | PA30864 |
| KEGG ID | hsa:4311 |
| BioCyc | |
| Entrez Gene (Gene ID) | 4311 |
| DIP | |
| STRING | 9606ENSP00000353679 |
| MINT | |
| IntAct | P08473 |
| DMDM | 128062 |
| BREDNA | 342411 |
| Rectome | R-HSA-2022377 |
| SignaLink | |
| BindingDB | P08473 |
| Fingerprint type | F1_CV | AUC_CV | Accuracy_CV | Sensitivity_CV | Specificity_CV | F1_test | AUC_test | Accuracy_test | Sensitivity_test | Specificity_test | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.883 | 0.910 | 0.880 | 0.868 | 0.894 | 0.906 | 0.905 | 0.898 | 0.893 | 0.904 | Download |
| MACCS fingerprints | 0.918 | 0.944 | 0.913 | 0.940 | 0.882 | 0.950 | 0.986 | 0.941 | 0.963 | 0.910 | Download |
| Daylight fingerprints | 0.778 | 0.775 | 0.765 | 0.793 | 0.735 | 0.767 | 0.749 | 0.742 | 0.767 | 0.711 | Download |
| ECFP2 fingerprints | 0.950 | 0.957 | 0.946 | 0.995 | 0.894 | 0.948 | 0.952 | 0.941 | 0.981 | 0.892 | Download |
| ECFP4 fingerprints | 0.960 | 0.963 | 0.957 | 0.992 | 0.919 | 0.943 | 0.948 | 0.935 | 0.961 | 0.904 | Download |
| ECFP6 fingerprints | 0.949 | 0.964 | 0.946 | 0.966 | 0.925 | 0.938 | 0.942 | 0.930 | 0.951 | 0.904 | Download |
| Positive dataset | Negative dataset |
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School of Pharmaceutical Sciences, Central South University.
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