Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
| Uniprot primary ID | P29274 |
| PDB ID | 4UG2 3EML 3QAK 1UPE 3PWH 1MMH 3VGA 4UHR 2YDO 3REY 3VG9 2YDV 4EIY 3RFM 3UZC 3UZA |
| DrugBank ID | DB00651 DB00640 DB06213 DB01412 DB00201 DB00824 DB00806 DB00358 DB04932 DB01303 DB00277 |
| BioGrid ID | 106647 |
| GuidetoPHARMACOLOGY ID | 19 |
| PharmGKB ID | PA24584 |
| KEGG ID | hsa:135 |
| BioCyc | |
| Entrez Gene (Gene ID) | 135 |
| DIP | |
| STRING | 9606ENSP00000336630 |
| MINT | MINT-4823612 |
| IntAct | P29274 |
| DMDM | 543740 |
| BREDNA | |
| Rectome | R-HSA-187024 R-HSA-418555 R-HSA-417973 |
| SignaLink | |
| BindingDB | P29274 |
| Fingerprint type | F1_CV | AUC_CV | Accuracy_CV | Sensitivity_CV | Specificity_CV | F1_test | AUC_test | Accuracy_test | Sensitivity_test | Specificity_test | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.873 | 0.905 | 0.873 | 0.872 | 0.874 | 0.873 | 0.901 | 0.872 | 0.875 | 0.870 | Download |
| MACCS fingerprints | 0.836 | 0.904 | 0.827 | 0.879 | 0.774 | 0.846 | 0.909 | 0.835 | 0.887 | 0.782 | Download |
| Daylight fingerprints | 0.793 | 0.802 | 0.793 | 0.792 | 0.793 | 0.775 | 0.790 | 0.779 | 0.757 | 0.801 | Download |
| ECFP2 fingerprints | 0.904 | 0.951 | 0.902 | 0.918 | 0.886 | 0.909 | 0.956 | 0.905 | 0.941 | 0.869 | Download |
| ECFP4 fingerprints | 0.896 | 0.953 | 0.900 | 0.858 | 0.941 | 0.917 | 0.962 | 0.917 | 0.902 | 0.932 | Download |
| ECFP6 fingerprints | 0.878 | 0.950 | 0.885 | 0.819 | 0.952 | 0.900 | 0.957 | 0.904 | 0.860 | 0.950 | Download |
| Positive dataset | Negative dataset |
Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University.
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