Target name

P50052: Type-2 angiotensin II receptor


  Protein function

Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation.

  Database links

Uniprot primary ID P50052
PDB ID
DrugBank ID DB01349
BioGrid ID 106692
GuidetoPHARMACOLOGY ID 35
PharmGKB ID PA44
KEGG ID hsa:186
BioCyc
Entrez Gene (Gene ID) 186
DIP
STRING 9606ENSP00000360973
MINT
IntAct P50052
DMDM 1703214
BREDNA
Rectome R-HSA-418594 R-HSA-375276
SignaLink
BindingDB P50052

  Model Performance Metrics

Fingerprint type F1_CV AUC_CV Accuracy_CV Sensitivity_CV Specificity_CV F1_test AUC_test Accuracy_test Sensitivity_test Specificity_test Download model
FP2 fingerprints 0.900 0.924 0.908 0.822 0.994 0.938 0.951 0.943 0.893 0.989 Download
MACCS fingerprints 0.827 0.906 0.837 0.779 0.894 0.825 0.896 0.840 0.786 0.890 Download
Daylight fingerprints 0.885 0.894 0.888 0.860 0.917 0.886 0.921 0.891 0.881 0.901 Download
ECFP2 fingerprints 0.951 0.987 0.953 0.914 0.991 0.931 0.987 0.937 0.881 0.989 Download
ECFP4 fingerprints 0.954 0.986 0.956 0.914 0.997 0.937 0.974 0.943 0.881 1.000 Download
ECFP6 fingerprints 0.946 0.969 0.948 0.897 1.000 0.923 0.952 0.931 0.857 1.000 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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