Motor protein required for establishing a bipolar spindle. Blocking of KIF11 prevents centrosome migration and arrest cells in mitosis with monoastral microtubule arrays.
| Uniprot primary ID | P52732 |
| PDB ID | 2XAE 4B7B 2FL2 2IEH 2FL6 3K5E 3K3B 4BXN 2X7C 4A50 4A51 2X7E 2X7D 3KEN 3L9H 3WPN 3HQD 2WOG 2FKY 1YRS 2FME 2UYM 2UYI 4AS7 4AQV 4AQW 3CJO 2PG2 4BBG 3ZCW 2GM1 2G1Q 2X2R 4AP0 1Q0B 1II6 2Q2Y 2Q2Z 4A1Z 4A28 4CK6 4CK7 4CK5 1X88 4A5Y |
| DrugBank ID | |
| BioGrid ID | 110030 |
| GuidetoPHARMACOLOGY ID | 2788 |
| PharmGKB ID | PA30177 |
| KEGG ID | hsa:3832 |
| BioCyc | |
| Entrez Gene (Gene ID) | 3832 |
| DIP | |
| STRING | 9606ENSP00000260731 |
| MINT | MINT-1152202 |
| IntAct | P52732 |
| DMDM | 116242604 |
| BREDNA | 3644 |
| Rectome | R-HSA-983189 R-HSA-2132295 |
| SignaLink | |
| BindingDB | P52732 |
| Fingerprint type | F1_CV | AUC_CV | Accuracy_CV | Sensitivity_CV | Specificity_CV | F1_test | AUC_test | Accuracy_test | Sensitivity_test | Specificity_test | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.818 | 0.875 | 0.821 | 0.798 | 0.845 | 0.832 | 0.890 | 0.837 | 0.813 | 0.860 | Download |
| MACCS fingerprints | 0.671 | 0.753 | 0.675 | 0.658 | 0.693 | 0.739 | 0.799 | 0.728 | 0.781 | 0.676 | Download |
| Daylight fingerprints | 0.704 | 0.784 | 0.726 | 0.647 | 0.806 | 0.780 | 0.861 | 0.796 | 0.725 | 0.866 | Download |
| ECFP2 fingerprints | 0.871 | 0.940 | 0.869 | 0.882 | 0.855 | 0.901 | 0.952 | 0.901 | 0.901 | 0.901 | Download |
| ECFP4 fingerprints | 0.897 | 0.948 | 0.896 | 0.898 | 0.894 | 0.911 | 0.961 | 0.913 | 0.895 | 0.930 | Download |
| ECFP6 fingerprints | 0.882 | 0.939 | 0.883 | 0.868 | 0.899 | 0.916 | 0.962 | 0.918 | 0.889 | 0.948 | Download |
| Positive dataset | Negative dataset |
Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University.
All rights reserved.
The recommended browsers: Safari, Firefox, Chrome,IE(Ver.>8).
E-mail: biomed@csu.edu.cn
 |
 |
 |
 |
 |
 |