Catalyzes the first glycosylation step in glycosphingolipid biosynthesis, the transfer of glucose to ceramide. May also serve as a "flippase".
| Uniprot primary ID | Q16739 |
| PDB ID | |
| DrugBank ID | DB00419 |
| BioGrid ID | 113204 |
| GuidetoPHARMACOLOGY ID | 2528 |
| PharmGKB ID | PA37169 |
| KEGG ID | hsa:7357 |
| BioCyc | |
| Entrez Gene (Gene ID) | 7357 |
| DIP | |
| STRING | 9606ENSP00000363397 |
| MINT | |
| IntAct | |
| DMDM | 2498228 |
| BREDNA | 24180 |
| Rectome | R-HSA-1660662 |
| SignaLink | |
| BindingDB | Q16739 |
| Fingerprint type | F1_CV | AUC_CV | Accuracy_CV | Sensitivity_CV | Specificity_CV | F1_test | AUC_test | Accuracy_test | Sensitivity_test | Specificity_test | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.936 | 0.952 | 0.935 | 0.927 | 0.943 | 0.968 | 0.969 | 0.963 | 0.938 | 1.000 | Download |
| MACCS fingerprints | 0.919 | 0.970 | 0.917 | 0.927 | 0.906 | 0.968 | 1.000 | 0.963 | 0.938 | 1.000 | Download |
| Daylight fingerprints | 0.932 | 0.936 | 0.935 | 0.873 | 1.000 | 0.968 | 0.969 | 0.963 | 0.938 | 1.000 | Download |
| ECFP2 fingerprints | 0.887 | 0.929 | 0.889 | 0.855 | 0.925 | 0.933 | 0.969 | 0.926 | 0.875 | 1.000 | Download |
| ECFP4 fingerprints | 0.904 | 0.950 | 0.907 | 0.855 | 0.962 | 0.933 | 0.969 | 0.926 | 0.875 | 1.000 | Download |
| ECFP6 fingerprints | 0.911 | 0.949 | 0.917 | 0.836 | 1.000 | 0.968 | 0.969 | 0.963 | 0.938 | 1.000 | Download |
| Positive dataset | Negative dataset |
Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University.
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