Details-Calcnet-AlzheimerNet

Target name

P49682: C-X-C chemokine receptor type 3

Protein function

Isoform 1: Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of human mesangial cells (HMC) through a heterotrimeric G-protein signaling pathway (PubMed:

Database links

Uniprot primary ID	P49682
PDB ID
DrugBank ID
BioGrid ID	109094
GuidetoPHARMACOLOGY ID	70
PharmGKB ID	PA35049
KEGG ID	hsa:2833
BioCyc
Entrez Gene (Gene ID)	2833
DIP	DIP-5891N
STRING	9606ENSP00000362795
MINT	MINT-91399
IntAct
DMDM	2829400
BREDNA
Rectome	R-HSA-418594 R-HSA-380108
SignaLink
BindingDB	P49682

Model Performance Metrics

Fingerprint type	F1_CV	AUC_CV	Accuracy_CV	Sensitivity_CV	Specificity_CV	F1_test	AUC_test	Accuracy_test	Sensitivity_test	Specificity_test	Download model
FP2 fingerprints	0.888	0.930	0.890	0.871	0.909	0.896	0.936	0.895	0.871	0.921	Download
MACCS fingerprints	0.849	0.917	0.841	0.886	0.795	0.867	0.933	0.862	0.889	0.833	Download
Daylight fingerprints	0.810	0.835	0.819	0.768	0.871	0.845	0.872	0.852	0.782	0.926	Download
ECFP2 fingerprints	0.943	0.975	0.942	0.962	0.922	0.955	0.990	0.954	0.955	0.952	Download
ECFP4 fingerprints	0.963	0.981	0.962	0.973	0.951	0.963	0.985	0.962	0.955	0.968	Download
ECFP6 fingerprints	0.960	0.983	0.960	0.963	0.956	0.960	0.986	0.959	0.950	0.968	Download

Download datasets

Positive dataset

Negative dataset